Sunday, December 30, 2012

Drug Eluting stents and disadvantages- can we overcome these?

Drug Eluting Stents for coronary arteries

The use of metal Drug Eluting Stents (DES) presents some potential drawbacks. These include a predisposition to late stent thrombosis, prevention of late vessel adaptive or expansive remodeling, hindrance of surgical re-vascularization, and impairment of imaging with multi slice CT. That means we need some thing better than this in future. Are we there yet? However, it has been hypothesized that stents placed in many atherosclerotic arteries may require only about 3–6 months of mechanical integrity for scaffolding. Bioabsorbable or biodegradable stents that provide mechanical support during vascular wall repair and then harmlessly erode after the vascular wall has stabilized may eliminate some of the potential chronic risks of permanent stents and may mitigate the complexity of repeat stenting at the same site in the event of restenosis.