Friday, June 09, 2017

Intra aortic thrombosis and peripheral arterial thrombosis in a person taking antipsychotic drugs





Fig: Angiogram films before and after therapy.

This patient was admitted with history of B/L lower limb ischemic pain ( sub acute ) while he was taking anti psychotic medications. Angiogram showed multi segmental thrombosis of the lower limb arteries. He was informed about the options - Thrombectomy and Medical therapies or combination. He opted for only medical therapies with Heparin, Prostaglandin E1 therapies. He was given monthly infections of PGE1 and antiplatelet drugs along with other antipsychotic medications. His symptoms disappeared. Now, he is able to walk freely for 2 km and after that he develops calf claudication due to the residual ischemia ( popliteal, tibial arterial residual occlusions)

Reference
http://onlinelibrary.wiley.com/doi/10.1111/pcn.12001/abstract